Optical Sensing Group

Contact

Dr Alex Thompson

Office B411, Bessemer Building,
South Kensington Campus

What we do

We use optical spectroscopy to develop new and improved diagnostic tools. This includes techniques such as fluorescence, Raman and diffuse reflectance spectroscopy, and involves the development of devices ranging from wearable sensors through to fibre-optic probes.

Why it is important

Our research has a number of potential clinical applications including improved monitoring of clinical therapies and interventions (e.g. in inflammatory bowel disease and malnutrition), early diagnosis of infection, and even margin mapping in tumour resection surgery.

How it can benefit patients

The devices we are developing can potentially provide less invasive and lower cost diagnostics. In turn, this may facilitate patient benefits including earlier diagnosis, earlier identification of relapse (e.g. in therapy response monitoring applications), more widespread deployment and more comfortable patient experiences (e.g. through use of less invasive probes and sensors).

Summary of current research

Key research projects currently underway include: fluorescence spectroscopy for non-invasive assessment of gut function; Raman spectroscopy for point-of-care identification of urine infections; and development of fibre-optic Raman probes for in vivo diagnostics.

Tabs - Funders / Etc

Related Centres

Collaborators

Key internal collaborators include:

The group also has numerous further internal and external collaborators through the HUNGer project.

Researchers

Name

Title

Department

Agarwal, Arjun

Undergraduate

Faculty of Medicine

Avery, James P

Imperial College Research Fellow

Department of Surgery & Cancer

Ezzat, Ahmed

Clinical Research Fellow

Department of Surgery & Cancer

Fletcher, Edward O

Clinical Research Fellow

Department of Surgery & Cancer

Mandal, Nilanjan

Research Associate in Optical Sensing for LMICs

Department of Surgery & Cancer

Monfort Sanchez, Elena

Research Postgraduate

Department of Surgery & Cancer

Thompson, Alexander J

Lecturer in Sensing in Cancer

Department of Surgery & Cancer

Wang, Zeyu

Research Postgraduate

Department of Surgery & Cancer

Wang, Zixin

Research Postgraduate

Department of Surgery & Cancer

Wei, Jonathan G J

Clinical Research Fellow

Department of Surgery & Cancer

Clinical Trials

We are currently running one clinical trial investigating the use of fluorescence spectroscopy for non-invasive assessment of gut health. Details can be found here.  

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